Calendar An icon of a desk calendar. Cancel An icon of a circle with a diagonal line across. Caret An icon of a block arrow pointing to the right. Email An icon of a paper envelope. Facebook An icon of the Facebook "f" mark. Google An icon of the Google "G" mark. Linked In An icon of the Linked In "in" mark. Logout An icon representing logout. Profile An icon that resembles human head and shoulders. Telephone An icon of a traditional telephone receiver. Tick An icon of a tick mark. Is Public An icon of a human eye and eyelashes. Is Not Public An icon of a human eye and eyelashes with a diagonal line through it. Pause Icon A two-lined pause icon for stopping interactions. Quote Mark A opening quote mark. Quote Mark A closing quote mark. Arrow An icon of an arrow. Folder An icon of a paper folder. Breaking An icon of an exclamation mark on a circular background. Camera An icon of a digital camera. Caret An icon of a caret arrow. Clock An icon of a clock face. Close An icon of the an X shape. Close Icon An icon used to represent where to interact to collapse or dismiss a component Comment An icon of a speech bubble. Comments An icon of a speech bubble, denoting user comments. Comments An icon of a speech bubble, denoting user comments. Ellipsis An icon of 3 horizontal dots. Envelope An icon of a paper envelope. Facebook An icon of a facebook f logo. Camera An icon of a digital camera. Home An icon of a house. Instagram An icon of the Instagram logo. LinkedIn An icon of the LinkedIn logo. Magnifying Glass An icon of a magnifying glass. Search Icon A magnifying glass icon that is used to represent the function of searching. Menu An icon of 3 horizontal lines. Hamburger Menu Icon An icon used to represent a collapsed menu. Next An icon of an arrow pointing to the right. Notice An explanation mark centred inside a circle. Previous An icon of an arrow pointing to the left. Rating An icon of a star. Tag An icon of a tag. Twitter An icon of the Twitter logo. Video Camera An icon of a video camera shape. Speech Bubble Icon A icon displaying a speech bubble WhatsApp An icon of the WhatsApp logo. Information An icon of an information logo. Plus A mathematical 'plus' symbol. Duration An icon indicating Time. Success Tick An icon of a green tick. Success Tick Timeout An icon of a greyed out success tick. Loading Spinner An icon of a loading spinner. Facebook Messenger An icon of the facebook messenger app logo. Facebook An icon of a facebook f logo. Facebook Messenger An icon of the Twitter app logo. LinkedIn An icon of the LinkedIn logo. WhatsApp Messenger An icon of the Whatsapp messenger app logo. Email An icon of an mail envelope. Copy link A decentered black square over a white square.

New drug slows Alzheimer’s progress, research reveals

(PA)
(PA)

Brain deterioration caused by Alzheimer’s has been delayed with a drug for the first time, researchers have announced.

Scientists trialling a new treatment called LMTX managed to slow the progression of the disease over 15 months.

The study found that when the drug was the only treatment patients took, it had a beneficial effect on key measures of Alzheimer’s – such as memory – for those with mild or moderate forms of the disease.

The small trial of 136 patients saw participants take the drug, leuco-methylthioninium-bis (hydromethanesulfonate), as a pill twice a day.

Alongside other drugs, LMTX was not as effective (Fiona Hanson/PA)
Alongside other drugs, LMTX was not as effective (Fiona Hanson/PA)

However, in a bigger trial, patients taking other drugs alongside LMTX did not see the same benefit.

Serge Gauthier from McGill University in Canada presented the results at the Alzheimer’s Association International Conference in Toronto.

He said: “In a study of this size across a combined mild to moderate patient population, it is both encouraging to see improvements of this magnitude in the standard cognitive and functional tests and reassuring to see the supporting brain scan evidence of a slowing in disease progression during 15 months of treatment.

“As a practising clinician I see Alzheimer’s patients, their families and care-givers every day, and continually share their desperate need for a truly therapeutic product as today we only have symptomatic treatments available to us.

“I am excited about the promise of LMTX as a potential new treatment option for these patients.”

The drug still has further trials to go through (Seth Wenig/AP)
The drug still has further trials to go through (Seth Wenig/AP)

Speaking to The Times he added: “This is the first time it has happened in our field that a drug reduced the rate of brain atrophy.”

Claude Wischik, from the University of Aberdeen, invented the drug and told the newspaper that he hoped to apply for a licence after publishing the results of a second trial.

LMTX (also called LMTM) is based on the structure of a chemical called methylene blue which is used as a dye in research and to aid surgery.

It works by tackling problems linked to proteins called tau that occur in Alzheimer’s sufferers.


READ MORE

Families urged to spend quality time together in support of Alzheimer’s charity

Alzheimer Scotland’s dementia gardens are beginning to blossom

 

//